The Colloidal Oatmeal that we use is manufactured by a unique patented process whereby the coarse whole oat flour is extruded prior to being fine milled to the USP particle size specification. It has been scientifically tested and demonstrated to have increased water binding capacity to standard colloidal oatmeal. This enhanced capacity to absorb water helps binds up to 88% more water than standard colloidal oatmeal.

Clinical Study

In-vitro cell biology testing found that our supplier’s colloidal oatmeal strongly stimulated production of fibroblasts, keratinocytes and structural proteins used in skin repair. To prove this has a practical application, an in-vivo study was conducted to assess the ability of our supplier’s colloidal oatmeal to repair the skin.

In-Vivo Skin Repair Study

A 5-day clinical study was conducted to ascertain the effects of our supplier’s colloidal oatmeal on already inflamed skin. A total of 15 subjects were tested over a period of 10 days. Two skin areas on the volar forearm were pre-irritated with 2% aqueous sodium lauryl sulphate (SLS). The skin was then treated with our supplier’s colloidal oatmeal versus a placebo containing no colloidal oatmeal and measurements for skin moisturisation, skin barrier function, skin colour and visual scoring of erythema were taken over 5 days.

Effect on Trans epidermal Water Loss (TEWL):

As the study progressed a decrease in TEWL was seen indicating barrier repair. Analysis of the relative performance of the 2 formulations showed that the Oat COM formulation TEWL values were significantly lower than those of the control formulation. This is indicative of accelerated barrier recovery compared to the placebo formulation.

Effect on Skin Hydration:

The mean values for the Corneometer measurement of skin surface moisture for our supplier’s formulation were higher than those with Placebo formulation during the study. This shows that our supplier’s colloidal oatmeal has benefits in terms of skin surface moisturisation.

Effect on Skin Redness:

The mean values for the Chromameter measurement of skin surface redness for our supplier’s colloidal oatmeal were lower than those with Placebo formulation during the study, demonstrating that our supplier’s colloidal oatmeal reduces skin surface redness. the clinical assessment of erythema for our supplier’s colloidal oatmeal were lower than those with Placebo formulation during the study, with statistically lower values measured at Day 1, Day 5 and for AUC, using Wilcoxon Rank Sum test. This data shows our supplier’s colloidal oatmeal leads to visible improvements in skin redness from first application and with sustained improvement, relative to the placebo.

CONCLUSION

In conclusion, the in-vivo skin repair Studies demonstrated that our supplier’s colloidal oatmeal leads to visible improvements in skin redness and scaliness, accelerated barrier recovery and enhanced moisturisation compared to the placebo formulation.

TEWL, hydration capacitance and erythema reduction all showed statistically significantly improved results after day 1 with our supplier’s colloidal oatmeal compared to the placebo, showing that our supplier’s colloidal oatmeal increases the overall skin repair capability.

Clinical Assessment of Erythema:

The mean values for the clinical assessment of erythema for our supplier’s colloidal oatmeal were lower than those with Placebo formulation during the study, with statistically lower values measured at Day 1, Day 5 and for AUC, using Wilcoxon Rank Sum test. This data shows that our supplier’s colloidal oatmeal leads to visible improvements in skin redness from first application and with sustained improvement, relative to the placebo formulation.

 

Independently tested by Chemex Environmental International Ltd September 2020.